February 2026
This podcast episode discusses a retrospective study comparing awake versus asleep surgery for high-grade glioma, demonstrating that while awake procedures allow for more extensive “supramaximal” resection and longer survival, they are uniquely linked to a transient drop in attention at one week post-op, that recovers to baseline by 1 month. The conversation highlights how exceeding a 61% resection threshold in non-contrast-enhanced areas or impacting the left default mode network predicts this temporary deficit, which typically resolves by the one-month follow-up. Please join us for this interesting discussion where we consider the implications and challenges of mapping and preserving attention during awake surgery.
Authors: Silvio Sarubbo and Luca Zigiotto
Guest Faculty: Pablo Valdes
Resident Planner: Alexander Himstead
Podcast Committee Vice Chair/Moderator: Martin Pham
